In 45 minutes: Your body increases production of the pleasure neurotransmitter dopamine.
In 60 minutes: The soda’s phosphoric acid binds with calcium, magnesium, and zinc in your lower intestine to give you a further boost in metabolism. This is intensified by the high doses of sugar and artificial sweeteners that also cause you to urinate out calcium.
After 60 minutes: The caffeine’s diuretic effect makes you have to pee. When you do, you’ll pass on the bonded calcium, magnesium, and zinc that were headed to your bones, as well as sodium, electrolytes, and water.
Then a sugar crash begins, and you may become irritable and sluggish. You’ve now urinated out all of the water that was in the Coke, along with the nutrients that the phosphoric acid bonded to in your body that would have hydrated you or gone on to build strong bones and teeth.